Santamaría Martínez

Enrique Santamaría Martínez
Santamaría Martínez ,
Enrique
‘Understanding the role of proteins in the human brain’
Santamaría Martínez ,
Enrique
Head of the Unit

My interest has always been focused on protein biochemistry and proteomics. My thesis work (awarded in 2005) was focused on the identification of biomarkers of non-alcoholic steatohepatitis and hepatocarcinoma using proteomics, obtaining three patents during this period.
During my postdoctoral stage (2006-10), I was involved in a Sixth Framework  EU project (FP6) gaining extensive knowledge in proteogenomic strategies to improve the potency and safety of HSV-1 based-oncolytic vectors. As a complement of my scientific training, I completed a Master in Business Management of SMEs (2008). In 2011, I moved to Navarrabiomed Biomedical Research Center (Miguel Servet Foundation, Pamplona, Spain) to establish a research unit focused on the characterization of neurodegenerative proteinopathies dealing with protein expression profiling, multiomics, postranslation modifications, drug repositioning and protein-protein interactions involved in neurological syndromes.

Throughout my scientific career, I have contributed in more than 160 papers, 25 chapter books, and edited three books about cerebrospinal fluid and brain proteomics. I have more than 15 years of experience in leading, mentoring and coaching scientists at all levels of education, being Assistant Professor in several National Biomedical Masters, Associate Professor at Health Sciences Department (UPNA) and directing 8 PhD thesis and multiple master degrees’students.

Targeted theses
Andrea González-Morales
Molecular study of glioblastoma multiforme cells treated with the oncolytic adenovirus Delta-24-RGD.
Mercedes Lachén-Montes
Olfaction and neurodegeneration: Olfactory Proteotyping across Proteinopathies.
Virginia Sánchez Quiles
Estudio de la función de Prohibitina-1 en la regulación de la proliferación y muerte celular. Implicaciones en procesos de daño hepático.
Maria Victoria Zelaya
Anatomo-proteomic study of the olfactory bulb in different stages of sporadic Alzheimer´s disease. Identification of common and distinct olfactory targets across Alzheimer´s disease copathologies.
Scientific-Technical Services