Translational Cardiology

The Translational Cardiology Unit at Navarrabiomed is formed by a consolidated work team in which professionals with diverse profiles (biologists, nurses, pharmacists, technicians, clinical cardiologists and cardiac surgeons) complement each other to develop research projects whose working hypotheses are based on the clinical needs of patients.

Our priority research lines are as follows:

• Study of sex-specific mechanisms in the development of valvular diseases: aortic stenosis, aortic insufficiency and mitral valvulopathy.
• Identification of new therapeutic targets in valvular diseases. Specifically, analysis of the aldosterone/mineralocorticoid receptor pathway and its targets galectin-3 and lipocalin-2 (NGAL).
• Study of circulating biomarkers of progression and response to treatment in valvular diseases.
• Analysis of the interactions between valvular diseases and chronic kidney disease and diabetes.
• New strategies for the treatment of infectious endocarditis.